Opisthorchis viverrini and Clonorchis sinensis, the 2 major species of small liver flukes family Opisthorchiidae , cause chronic inflammation in the bile duct, which leads to cholangitis and cirrhosis of the liver, and are a predisposing factor for cholangiocarcinoma 1.
Human infections with O. During β, two of Cambodian refugees in the United States were found to be positive for C. Egg-positive cases were later detected in several provinces of Cambodia 4 , 5. We found an egg-positive rate of Because these eggs may be those of Haplorchis spp. Six of the small trematode eggβpositive villagers, 1 man and 5 women age range 16β72 years , who had occasional epigastric discomfort were selected for anthelmintic treatment, purgation, and recovery of adult worms.
Fecal examination and anthelmintic treatment of villagers were approved by the Ministry of Health, Cambodia, under the agreement with the KoreaβCambodia International Collaboration on Intestinal Parasite Control in Cambodia β Feces was obtained 3 or 4 times in a 2β3-hour period after purgation, pooled individually, and processed as described 7. A Adult Opisthorchis viverrini liver fluke length A total of 34 O.
No other species of trematodes were obtained. Five worms were lanceolate and had a mean length of 9. A total of 50 metacercariae Figure , panel B were obtained from 5 P. Six weeks later, 42 young O. Our study identified only O. However, eggs of other hepatic and intestinal flukes also can be found in humans 1.
In a mountainous area of Phongsaly Province, H. Thus, in Cambodia, the presence of human infections with intestinal flukes, including Haplorchis spp.
